histoplasmosis is defined as infection by the fungus Histoplasma capsulatum. His story begins in 1906 with the major histopathological findings made by Darling in which it noted "a parasite egg-shaped to round, surrounded by a halo that is not colored, with a thickness of about 1 / 6 the diameter of the parasite." Due to the similarity with Leishmania, thought it was a protozoan, and the halo was a capsule, so it called Histoplasma capsulatum. is a dimorphic fungus that at temperatures below 35 ° C grown in culture media as a white filamentous fungus, whereas at 37 ° C, both in vitro and in host tissues, growth is yeast.
Since 1987, histoplasmosis is included among the markers of AIDS opportunistic infections and their incidence among HIV-positive varies from one region to another.
Add too, that when the clinic between the predominant signs and symptoms include fever and hepatomegaly (100% and 92% respectively) are also common fatigue, weight loss, anorexia and axillary and cervical lymphadenopathy (67%). Cutaneous manifestations due to their high frequency of occurrence (58%) have led not infrequently to clinical diagnosis and microbiological diagnosis confirmed by isolation of H. capsulatum from samples skin biopsies. About
1904, along with Drs Darling Gorgas and Le Prince, also pioneered in malaria control, having obtained outstanding achievements in the etiology, epidemiology, therapy, and prophylaxis of malaria during construction of the Panama Canal.
Author: RIBERA MARTÍ, CRISTINA.
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